JAG2/Notch2 inhibits intervertebral disc degeneration by modulating cell proliferation, apoptosis, and extracellular matrix

BACKGROUND: Intervertebral disc degeneration (IVDD)-related disorders are the major causes of low back pain. A previous study suggested that Notch activation serves as a protective mechanism and is a part of the compensatory response that maintains the necessary resident nucleus pulposus (NP) cell p...

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Bibliografiske detaljer
Udgivet i:Arthritis Res Ther
Main Authors: Long, Jun, Wang, Xiaobo, Du, Xianfa, Pan, Hehai, Wang, Jianru, Li, Zemin, Liu, Hui, Li, Xudong, Zheng, Zhaomin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796488/
https://ncbi.nlm.nih.gov/pubmed/31619270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-019-1990-z
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