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The caudate nucleus undergoes dramatic and unique transcriptional changes in human prodromal Huntington’s disease brain
BACKGROUND: The mechanisms underlying neurodegeneration in the striatum of Huntingon’s Disease (HD) brain are currently unknown. While the striatum is massively degenerated in symptomatic individuals, which makes cellular characterization difficult, it is largely intact in asymptomatic HD gene posit...
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| Veröffentlicht in: | BMC Med Genomics |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6796419/ https://ncbi.nlm.nih.gov/pubmed/31619230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0581-9 |
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