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The caudate nucleus undergoes dramatic and unique transcriptional changes in human prodromal Huntington’s disease brain
BACKGROUND: The mechanisms underlying neurodegeneration in the striatum of Huntingon’s Disease (HD) brain are currently unknown. While the striatum is massively degenerated in symptomatic individuals, which makes cellular characterization difficult, it is largely intact in asymptomatic HD gene posit...
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| Publicado no: | BMC Med Genomics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6796419/ https://ncbi.nlm.nih.gov/pubmed/31619230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0581-9 |
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