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P11.38 The Galectin-1 inhibitor OTX-008 has antiproliferative effects on human glioblastoma cells independent of MGMT-promotor status

BACKGROUND: The protein Galectin-1 (gal-1) is known to be involved in proliferation and progression of several malignancies. The allosteric gal-1 inhibitor OTX-008 has an antiproliferative effect on various tumors in vitro and in vivo. However, the effect of OTX-008 on patient derived GBM cultures i...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Goett, H, Kolodziej, M, Pons-Kühnemann, J, Schwarm, F, Koch, C, Uhl, E, Stein, M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796109/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.184
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