Short-Long Heart Rate Variation Increases Dispersion of Action Potential Duration in Long QT Type 2 Transgenic Rabbit Model

The initiation of polymorphic ventricular tachycardia in long QT syndrome type 2 (LQT2) has been associated with a characteristic ECG pattern of short-long RR intervals. We hypothesize that this characteristic pattern increases APD dispersion in LQT2, thereby promoting arrhythmia. We investigated AP...

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Vydáno v:Sci Rep
Hlavní autoři: Kim, Tae Yun, Jeng, Paul, Hwang, JungMin, Pfeiffer, Zachary, Patel, Divyang, Cooper, Leroy L, Kossidas, Konstantinos, Centracchio, Jason, Peng, Xuwen, Koren, Gideon, Qu, Zhilin, Choi, Bum-Rak
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795902/
https://ncbi.nlm.nih.gov/pubmed/31619700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51230-9
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