Imbalance in the response of pre- and post-synaptic components to amyloidopathy

Alzheimer’s disease (AD)-associated synaptic dysfunction drives the progression of pathology from its earliest stages. Amyloid β (Aβ) species, both soluble and in plaque deposits, have been causally related to the progressive, structural and functional impairments observed in AD. It is, however, sti...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Stephen, Terri-Leigh, Tamagnini, Francesco, Piegsa, Judith, Sung, Katherine, Harvey, Joshua, Oliver-Evans, Alice, Murray, Tracey K., Ahmed, Zeshan, Hutton, Michael L., Randall, Andrew, O’Neill, Michael J., Jackson, Johanna S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795896/
https://ncbi.nlm.nih.gov/pubmed/31619689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50781-1
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