P14.74 Remarkable response to Combined BRAF and MEK Inhibitors in two Adults with leptomeningeal carcinomatosis secondary to Pleomorphic Xantoastrocytoma grade II with BRAFv600E mutation

BACKGROUND: Several cancers with the BRAF V600E mutations have been successfully treated with targeted therapy. Pleomorphic xanthoastrocytoma (PXA) is a rare brain tumor, with an incidence of 0.07cases per 100,000. The BRAFV600 mutation is present in 38–60% of PXA. Typical treatment is gross total r...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Eoli, M, Pollo, B, Silvani, A, Paterra, R, Erbetta, A, Anghileri, E, Gaviani, P, Finocchiaro, G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2019
Konular:
Poster Presentations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795776/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.309
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