Streptozotocin-Induced Diabetic Neuropathic Pain Is Associated with Potentiated Calcium-Permeable AMPA Receptor Activity in the Spinal Cord

Neuronal hyperactivity in the spinal dorsal horn can amplify nociceptive input in diabetic neuropathic pain. The glutamate N‐methyl‐d‐aspartate and α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (NMDA receptors and AMPA receptors, respectively) are involved in spinal nociceptive tra...

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Veröffentlicht in:J Pharmacol Exp Ther
Hauptverfasser: Chen, Shao-Rui, Zhang, Jixiang, Chen, Hong, Pan, Hui-Lin
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2019
Schlagworte:
Neuropharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795745/
https://ncbi.nlm.nih.gov/pubmed/31481518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.261339
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