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Removal of the Potassium Chloride Co-Transporter from the Somatodendritic Membrane of Axotomized Motoneurons Is Independent of BDNF/TrkB Signaling But Is Controlled by Neuromuscular Innervation

The potassium-chloride cotransporter (KCC2) maintains the low intracellular chloride found in mature central neurons and controls the strength and direction of GABA/glycine synapses. We found that following axotomy as a consequence of peripheral nerve injuries (PNIs), KCC2 protein is lost throughout...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Akhter, Erica Tracey, Griffith, Ronald W., English, Arthur W., Alvarez, Francisco J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795555/
https://ncbi.nlm.nih.gov/pubmed/31541001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0172-19.2019
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