Antisense regulation of atrial natriuretic peptide expression

The cardiac hormone atrial natriuretic peptide (ANP) is a central regulator of blood volume and a therapeutic target in hypertension and heart failure. Enhanced ANP activity in such conditions through inhibition of the degradative enzyme neprilysin has shown clinical efficacy but is complicated by c...

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Publicat a:JCI Insight
Autors principals: Celik, Selvi, Sadegh, Mardjaneh Karbalaei, Morley, Michael, Roselli, Carolina, Ellinor, Patrick T., Cappola, Thomas, Smith, J. Gustav, Gidlöf, Olof
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795498/
https://ncbi.nlm.nih.gov/pubmed/31503546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130978
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