Resident memory CD8(+) T cells within cancer islands mediate survival in breast cancer patients

CD8(+) tumor-infiltrating lymphocytes (TILs) correlate with relapse-free survival (RFS) in most cancer types, including breast cancer. However, subset composition, functional status, and spatial location of CD8(+) TILs in relation to RFS in human breast tumors remain unclear. Spatial tissue analysis...

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Udgivet i:JCI Insight
Main Authors: Egelston, Colt A., Avalos, Christian, Tu, Travis Y., Rosario, Anthony, Wang, Roger, Solomon, Shawn, Srinivasan, Gayathri, Nelson, Michael S., Huang, Yinghui, Lim, Min Hui, Simons, Diana L., He, Ting-Fang, Yim, John H., Kruper, Laura, Mortimer, Joanne, Yost, Susan, Guo, Weihua, Ruel, Christopher, Frankel, Paul H., Yuan, Yuan, Lee, Peter P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795408/
https://ncbi.nlm.nih.gov/pubmed/31465302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130000
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