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Human breast tumor-infiltrating CD8(+) T cells retain polyfunctionality despite PD-1 expression
Functional CD8(+) T cells in human tumors play a clear role in clinical prognosis and response to immunotherapeutic interventions. PD-1 expression in T cells involved in chronic infections and tumors such as melanoma often correlates with a state of T-cell exhaustion. Here we interrogate CD8(+) tumo...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6191461/ https://ncbi.nlm.nih.gov/pubmed/30327458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06653-9 |
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