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Human breast tumor-infiltrating CD8(+) T cells retain polyfunctionality despite PD-1 expression
Functional CD8(+) T cells in human tumors play a clear role in clinical prognosis and response to immunotherapeutic interventions. PD-1 expression in T cells involved in chronic infections and tumors such as melanoma often correlates with a state of T-cell exhaustion. Here we interrogate CD8(+) tumo...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Commun |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group UK
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6191461/ https://ncbi.nlm.nih.gov/pubmed/30327458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06653-9 |
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