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Follicular lymphoma tumor–infiltrating T-helper (T(H)) cells have the same polyfunctional potential as normal nodal T(H) cells despite skewed differentiation

The follicular lymphoma (FL) T-cell microenvironment plays a critical role in the biology of this disease. We therefore determined the lineage, differentiation state, and functional potential of FL-infiltrating CD4(+) T-helper cells (T(H)) compared with reactive and normal lymph node (NLN) T(H) cell...

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Detalhes bibliográficos
Main Authors: Hilchey, Shannon P., Rosenberg, Alexander F., Hyrien, Ollivier, Secor-Socha, Shelley, Cochran, Matthew R., Brady, Michael T., Wang, Jyh-Chiang E., Sanz, Iñaki, Burack, W. Richard, Quataert, Sally A., Bernstein, Steven H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186335/
https://ncbi.nlm.nih.gov/pubmed/21821704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-340646
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