Visual Contrast Sensitivity Correlates to the Retinal Degeneration in Rhodopsin Knockout Mice

PURPOSE: Clinical manifestations of photoreceptor degeneration include gradual thinning of the outer nuclear layer (ONL) and progressive reduction of electroretinogram (ERG) amplitudes and vision loss. Although preclinical evaluations of treatment strategies greatly depend on rodent models, the cour...

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Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Xiao, Jiaxin, Adil, Muhammed Yasin, Chang, Karen, Yu, Zicheng, Yang, Lanbo, Utheim, Tor P, Chen, Dong Feng, Cho, Kin-Sang
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2019
Fag:
Physiology and Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795341/
https://ncbi.nlm.nih.gov/pubmed/31618423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.19-26966
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