iPSC-derived functional human neuromuscular junctions model the pathophysiology of neuromuscular diseases

The control of voluntary skeletal muscle contraction relies on action potentials, which send signals from the motor neuron through the neuromuscular junction (NMJ). Although dysfunction of the NMJ causes various neuromuscular diseases, a reliable in vitro system for disease modeling is currently una...

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Udgivet i:JCI Insight
Main Authors: Lin, Chuang-Yu, Yoshida, Michiko, Li, Li-Tzu, Ikenaka, Akihiro, Oshima, Shiori, Nakagawa, Kazuhiro, Sakurai, Hidetoshi, Matsui, Eriko, Nakahata, Tatsutoshi, Saito, Megumu K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795289/
https://ncbi.nlm.nih.gov/pubmed/31534050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124299
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