Monocyte glycolysis determines CD8(+) T cell functionality in human Chagas disease

Chagas disease is a lifelong pathology resulting from Trypanosoma cruzi infection. It represents one of the most frequent causes of heart failure and sudden death in Latin America. Herein, we provide evidence that aerobic glycolytic pathway activation in monocytes drives nitric oxide (NO) production...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:JCI Insight
Hlavní autoři: Sanmarco, Liliana María, Eberhardt, Natalia, Bergero, Gastón, Quebrada Palacio, Luz Piedad, Adami, Pamela Martino, Visconti, Laura Marina, Minguez, Ángel Ramón, Hernández-Vasquez, Yolanda, Silva, Eugenio Antonio Carrera, Morelli, Laura, Postan, Miriam, Aoki, Maria Pilar
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795286/
https://ncbi.nlm.nih.gov/pubmed/31479429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123490
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky