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OS6.3 The complex role of lactate dehydrogenases in glioblastoma development

BACKGROUND: Glioblastomas are among the most malignant primary brain tumors. GBMs are highly angiogenic, exhibit invasive growth, and elevated glycolysis. Under glycolytic conditions, glucose from the blood is metabolized in astrocytes into lactate by LDHA, and exported by MCT4 into the extracellula...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Daubon, T, Guyon, J, Chouleur, T, Espedal, H, Leon, C, Bjerkvig, R, Bikfalvi, A
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795110/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.041
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