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OS6.3 The complex role of lactate dehydrogenases in glioblastoma development
BACKGROUND: Glioblastomas are among the most malignant primary brain tumors. GBMs are highly angiogenic, exhibit invasive growth, and elevated glycolysis. Under glycolytic conditions, glucose from the blood is metabolized in astrocytes into lactate by LDHA, and exported by MCT4 into the extracellula...
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| Publicado en: | Neuro Oncol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6795110/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.041 |
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