Plumbagin Prevents Secretory Diarrhea by Inhibiting CaCC and CFTR Channel Activities

Secretory diarrhea, which primarily originates through intestinal pathogens and viruses, is a health burden in many regions worldwide. Enterocyte Cl(−) channels, as the final step in enterotoxin-induced fluid secretion, constitute an attractive class of targets for diarrhea therapy. Chloride channel...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Yu, Bo, Zhu, Xiaojuan, Yang, Xinyu, Jin, Lingling, Xu, Jia, Ma, Tonghui, Yang, Hong
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795057/
https://ncbi.nlm.nih.gov/pubmed/31649543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01181
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