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Plumbagin Prevents Secretory Diarrhea by Inhibiting CaCC and CFTR Channel Activities

Secretory diarrhea, which primarily originates through intestinal pathogens and viruses, is a health burden in many regions worldwide. Enterocyte Cl− channels, as the final step in enterotoxin-induced fluid secretion, constitute an attractive class of targets for diarrhea therapy. Chloride channel i...

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Detalhes bibliográficos
Main Authors: Bo Yu, Xiaojuan Zhu, Xinyu Yang, Lingling Jin, Jia Xu, Tonghui Ma, Hong Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-10-01
Colecção:Frontiers in Pharmacology
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fphar.2019.01181/full
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