RGS4 Maintains Chronic Pain Symptoms in Rodent Models

Regulator of G-protein signaling 4 (RGS4) is a potent modulator of G-protein-coupled receptor signal transduction that is expressed throughout the pain matrix. Here, we use genetic mouse models to demonstrate a role of RGS4 in the maintenance of chronic pain states in male and female mice. Using par...

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Pubblicato in:J Neurosci
Autori principali: Avrampou, Kleopatra, Pryce, Kerri D., Ramakrishnan, Aarthi, Sakloth, Farhana, Gaspari, Sevasti, Serafini, Randal A., Mitsi, Vasiliki, Polizu, Claire, Swartz, Cole, Ligas, Barbara, Richards, Abigail, Shen, Li, Carr, Fiona B., Zachariou, Venetia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2019
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794935/
https://ncbi.nlm.nih.gov/pubmed/31308097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3154-18.2019
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