The CRISPR‐Cas13a Gene‐Editing System Induces Collateral Cleavage of RNA in Glioma Cells

RNA is rarely used as a therapeutic target due to its flexible structure and instability. CRISPR‐Cas13a is a powerful tool for RNA knockdown, and the potential application of CRISPR‐Cas13a in cancer cells should be further studied. In this study, overexpression of LwCas13a by lentivirus in glioma ce...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Adv Sci (Weinh)
Main Authors: Wang, Qixue, Liu, Xing, Zhou, Junhu, Yang, Chao, Wang, Guangxiu, Tan, Yanli, Wu, Ye, Zhang, Sijing, Yi, Kaikai, Kang, Chunsheng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794629/
https://ncbi.nlm.nih.gov/pubmed/31637166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.201901299
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados