Molecular mechanism of TRPV2 channel modulation by cannabidiol

Transient receptor potential vanilloid 2 (TRPV2) plays a critical role in neuronal development, cardiac function, immunity, and cancer. Cannabidiol (CBD), the non-psychotropic therapeutically active ingredient of Cannabis sativa, is an activator of TRPV2 and also modulates other transient receptor p...

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Pubblicato in:eLife
Autori principali: Pumroy, Ruth A, Samanta, Amrita, Liu, Yuhang, Hughes, Taylor ET, Zhao, Siyuan, Yudin, Yevgen, Rohacs, Tibor, Han, Seungil, Moiseenkova-Bell, Vera Y
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
Soggetti:
Structural Biology and Molecular Biophysics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794088/
https://ncbi.nlm.nih.gov/pubmed/31566564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48792
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