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Region-Specific Hierarchy between Atrophy, Hypometabolism, and β-Amyloid (Aβ) Load in Alzheimer's Disease Dementia

Gray matter atrophy, glucose hypometabolism, and β-amyloid Aβ deposition are well-described hallmarks of Alzheimer's disease, but their relationships are poorly understood. The present study aims to compare the local levels of these three alterations in humans with Alzheimer's disease. Str...

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Pubblicato in:J Neurosci
Autori principali: La Joie, Renaud, Perrotin, Audrey, Barré, Louisa, Hommet, Caroline, Mézenge, Florence, Ibazizene, Méziane, Camus, Vincent, Abbas, Ahmed, Landeau, Brigitte, Guilloteau, Denis, de La Sayette, Vincent, Eustache, Francis, Desgranges, Béatrice, Chételat, Gaël
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794030/
https://ncbi.nlm.nih.gov/pubmed/23152610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2170-12.2012
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