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Relationships between Hippocampal Atrophy, White Matter Disruption, and Gray Matter Hypometabolism in Alzheimer's Disease

In early Alzheimer's disease (AD), the hippocampal region is the area most severely affected by cellular and structural alterations, yet glucose hypometabolism predominates in the posterior association cortex and posterior cingulate gyrus. One prevalent hypothesis to account for this discrepanc...

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Main Authors: Villain, Nicolas, Desgranges, Béatrice, Viader, Fausto, de la Sayette, Vincent, Mézenge, Florence, Landeau, Brigitte, Baron, Jean-Claude, Eustache, Francis, Chételat, Gaël
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902815/
https://ncbi.nlm.nih.gov/pubmed/18550759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1392-08.2008
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