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Defining Affinity with the GABA(A) Receptor

At nicotinic and glutamatergic synapses, the duration of the postsynaptic response depends on the affinity of the receptor for transmitter (Colquhoun et al., 1977; Pan et al., 1993). Affinity is often thought to be determined by the ligand unbinding rate, whereas the binding rate is assumed to be di...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Jones, Mathew V., Sahara, Yoshinori, Dzubay, Jeffrey A., Westbrook, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793556/
https://ncbi.nlm.nih.gov/pubmed/9786967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-21-08590.1998
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