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The Sodium Channel Scn8a Is the Major Contributor to the Postnatal Developmental Increase of Sodium Current Density in Spinal Motoneurons

Sodium currents were recorded from motoneurons that were isolated from mice at postnatal days 0–8 (P0–P8) and maintained in culture for 12–24 hr. Motoneurons from normal mice exhibited a more than threefold increase in peak sodium current density from P0 to P8. For mice lacking a functional Scn8a so...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: García, Kelly D., Sprunger, Leslie K., Meisler, Miriam H., Beam, Kurt G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793491/
https://ncbi.nlm.nih.gov/pubmed/9651206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-14-05234.1998
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