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Mitochondrial Control of Acute Glutamate Excitotoxicity in Cultured Cerebellar Granule Cells

Mitochondria within cultured rat cerebellar granule cells have a complex influence on cytoplasmic free Ca(2+)([Ca(2+)](c)) responses to glutamate. A decreased initial [Ca(2+)](c)elevation in cells whose mitochondria are depolarized by inhibition of the ATP synthase and respiratory chain (conditions...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Castilho, Roger F., Hansson, Oskar, Ward, Manus W., Budd, Samantha L., Nicholls, David G.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793348/
https://ncbi.nlm.nih.gov/pubmed/9852565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-24-10277.1998
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