Chlorpyrifos Toxicity in Mouse Cultured Cerebellar Granule Neurons at Different Stages of Development: Additive Effect on Glutamate-Induced Excitotoxicity

OBJECTIVE: Chlorpyrifos (CPF) is a neurotoxic organophosphorus (OP) insecticide. Its mechanism of action includes oxidative stress, excitotoxicity, and inhibition of the acetylcholinesterase enzyme (AChE). The aim of the present study is to investigate CPF toxicity in mature and immature cerebellar...

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Vydáno v:Cell J
Hlavní autoři: Amani, Nahid, Soodi, Maliheh, Daraei, Bahram, Dashti, Abolfazl
Médium: Artigo
Jazyk:Inglês
Vydáno: Royan Institute 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5011335/
https://ncbi.nlm.nih.gov/pubmed/27602329
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