Perforin-Dependent Neurologic Injury in a Viral Model of Multiple Sclerosis

In this study we demonstrate perforin-mediated cytotoxic effector function is necessary for viral clearance and may directly contribute to the development of neurologic deficits after demyelination in the Theiler’s murine encephalomyelitis virus (TMEV) model of multiple sclerosis. We previously demo...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Murray, Paul D., McGavern, Dorian B., Lin, Xiaoqi, Njenga, M. Kariuki, Leibowitz, Julian, Pease, Larry R., Rodriguez, Moses
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 1998
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793251/
https://ncbi.nlm.nih.gov/pubmed/9736651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-18-07306.1998
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