Perforin-Dependent Neurologic Injury in a Viral Model of Multiple Sclerosis

In this study we demonstrate perforin-mediated cytotoxic effector function is necessary for viral clearance and may directly contribute to the development of neurologic deficits after demyelination in the Theiler’s murine encephalomyelitis virus (TMEV) model of multiple sclerosis. We previously demo...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Murray, Paul D., McGavern, Dorian B., Lin, Xiaoqi, Njenga, M. Kariuki, Leibowitz, Julian, Pease, Larry R., Rodriguez, Moses
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793251/
https://ncbi.nlm.nih.gov/pubmed/9736651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-18-07306.1998
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