A Protein Kinase, PKN, Accumulates in Alzheimer Neurofibrillary Tangles and Associated Endoplasmic Reticulum-Derived Vesicles and Phosphorylates Tau Protein

A possible role for a protein kinase, PKN, a fatty acid-activated serine/threonine kinase with a catalytic domain homologous to the protein kinase C family and a direct target for Rho, was investigated in the pathology of Alzheimer’s disease (AD) using a sensitive immunocytochemistry on postmortem h...

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Publicado en:J Neurosci
Autores principales: Kawamata, Toshio, Taniguchi, Taizo, Mukai, Hideyuki, Kitagawa, Michinori, Hashimoto, Takeshi, Maeda, Kiyoshi, Ono, Yoshitaka, Tanaka, Chikako
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1998
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793236/
https://ncbi.nlm.nih.gov/pubmed/9736660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-18-07402.1998
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