Biochemical and Morphometric Analyses Show that Myelination in the Insulin-like Growth Factor 1 Null Brain Is Proportionate to Its Neuronal Composition

To elucidate the role of insulin-like growth factor 1 (IGF1) in the normal development of brain myelination, we used behavioral, biochemical, and histological analyses to compare the myelination of brains from Igf1(−/−) and wild-type (WT) littermate mice. The studies were conducted at postnatal day...

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Publié dans:J Neurosci
Auteurs principaux: Cheng, Clara M., Joncas, George, Reinhardt, Rickey R., Farrer, Robert, Quarles, Richard, Janssen, Jeremy, McDonald, Michael P., Crawley, Jacqueline N., Powell-Braxton, Lynn, Bondy, Carolyn A.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1998
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793060/
https://ncbi.nlm.nih.gov/pubmed/9671658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-15-05673.1998
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