Biochemically altered myelin triggers autoimmune demyelination

Although immune attack against central nervous system (CNS) myelin is a central feature of multiple sclerosis (MS), its root cause is unresolved. In this report, we provide direct evidence that subtle biochemical modifications to brain myelin elicit pathological immune responses with radiological an...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Caprariello, Andrew V., Rogers, James A., Morgan, Megan L., Hoghooghi, Vahid, Plemel, Jason R., Koebel, Adam, Tsutsui, Shigeki, Dunn, Jeffrey F., Kotra, Lakshmi P., Ousman, Shalina S., Wee Yong, V., Stys, Peter K.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2018
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003499/
https://ncbi.nlm.nih.gov/pubmed/29728463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721115115
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