Biochemically altered myelin triggers autoimmune demyelination

Although immune attack against central nervous system (CNS) myelin is a central feature of multiple sclerosis (MS), its root cause is unresolved. In this report, we provide direct evidence that subtle biochemical modifications to brain myelin elicit pathological immune responses with radiological an...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Caprariello, Andrew V., Rogers, James A., Morgan, Megan L., Hoghooghi, Vahid, Plemel, Jason R., Koebel, Adam, Tsutsui, Shigeki, Dunn, Jeffrey F., Kotra, Lakshmi P., Ousman, Shalina S., Wee Yong, V., Stys, Peter K.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2018
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003499/
https://ncbi.nlm.nih.gov/pubmed/29728463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721115115
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