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Biochemically altered myelin triggers autoimmune demyelination

Although immune attack against central nervous system (CNS) myelin is a central feature of multiple sclerosis (MS), its root cause is unresolved. In this report, we provide direct evidence that subtle biochemical modifications to brain myelin elicit pathological immune responses with radiological an...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Caprariello, Andrew V., Rogers, James A., Morgan, Megan L., Hoghooghi, Vahid, Plemel, Jason R., Koebel, Adam, Tsutsui, Shigeki, Dunn, Jeffrey F., Kotra, Lakshmi P., Ousman, Shalina S., Wee Yong, V., Stys, Peter K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003499/
https://ncbi.nlm.nih.gov/pubmed/29728463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721115115
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