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Nitric Oxide Signaling in Pain and Nociceptor Sensitization in the Rat

We investigated the role of nitric oxide (NO) in inflammatory hyperalgesia. Coinjection of prostaglandin E(2)(PGE(2)) with the nitric oxide synthase (NOS) inhibitorN(G)-methyl-l-arginine (l-NMA) inhibited PGE(2)-induced hyperalgesia.l-NMA was also able to reverse that hyperalgesia. This suggests tha...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Aley, K. O., McCarter, Gordon, Levine, Jon D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792985/
https://ncbi.nlm.nih.gov/pubmed/9712669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-17-07008.1998
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