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Widespread Elimination of Naturally Occurring Neuronal Death inBax-Deficient Mice

The proapoptotic molecule BAX is required for death of sympathetic and motor neurons in the setting of trophic factor deprivation. Furthermore, adult Bax−/− mice have more motor neurons than do their wild-type counterparts. These findings raise the possibility that BAX regulates naturally occurring...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: White, Fletcher A., Keller-Peck, Cynthia R., Knudson, C. Michael, Korsmeyer, Stanley J., Snider, William D.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792725/
https://ncbi.nlm.nih.gov/pubmed/9454852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-04-01428.1998
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