Phosphatidylinositol 3-Kinase and Akt Protein Kinase Are Necessary and Sufficient for the Survival of Nerve Growth Factor-Dependent Sympathetic Neurons

Recent studies have suggested a role for phosphatidylinositol (PI) 3-kinase in cell survival, including the survival of neurons. We used rat sympathetic neurons maintained in vitro to characterize the potential survival signals mediated by PI 3-kinase and to test whether the Akt protein kinase, a pu...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Crowder, Robert J., Freeman, Robert S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1998
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792598/
https://ncbi.nlm.nih.gov/pubmed/9526010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-08-02933.1998
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