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Hexokinase 2 dimerization and interaction with voltage‐dependent anion channel promoted resistance to cell apoptosis induced by gemcitabine in pancreatic cancer

Gemcitabine (GEM) is the standard chemotherapy drug for pancreatic cancer. Because of widespread drug resistance, the effect is limited. Therefore, it is urgent to reveal the underlying mechanism. Glycolysis is the most remarkable character of tumor aberrant metabolism, which plays vital roles on tu...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Fan, Kun, Fan, Zhiyao, Cheng, He, Huang, Qiuyi, Yang, Chao, Jin, Kaizhou, Luo, Guopei, Yu, Xianjun, Liu, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792491/
https://ncbi.nlm.nih.gov/pubmed/31426130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2463
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