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Hexokinase 2 dimerization and interaction with voltage‐dependent anion channel promoted resistance to cell apoptosis induced by gemcitabine in pancreatic cancer

Gemcitabine (GEM) is the standard chemotherapy drug for pancreatic cancer. Because of widespread drug resistance, the effect is limited. Therefore, it is urgent to reveal the underlying mechanism. Glycolysis is the most remarkable character of tumor aberrant metabolism, which plays vital roles on tu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Med
Egile Nagusiak: Fan, Kun, Fan, Zhiyao, Cheng, He, Huang, Qiuyi, Yang, Chao, Jin, Kaizhou, Luo, Guopei, Yu, Xianjun, Liu, Chen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792491/
https://ncbi.nlm.nih.gov/pubmed/31426130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2463
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