Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Population-Based Analysis of Toxicokinetics and Kidney Toxicodynamics of Tetrachloroethylene

BACKGROUND: Interindividual variability in susceptibility remains poorly characterized for environmental chemicals such as tetrachloroethylene (PERC). Development of population-based experimental models provide a potential approach to fill this critical need in human health risk assessment. OBJECTIV...

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Pubblicato in:Environ Health Perspect
Autori principali: Luo, Yu-Syuan, Cichocki, Joseph A., Hsieh, Nan-Hung, Lewis, Lauren, Wright, Fred A., Threadgill, David W., Chiu, Weihsueh A., Rusyn, Ivan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Environmental Health Perspectives 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792382/
https://ncbi.nlm.nih.gov/pubmed/31246107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP5105
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