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3-Amino-chromanes and Tetrahydroquinolines as Selective 5-HT(2B), 5-HT(7), or σ(1) Receptor Ligands

[Image: see text] The phenethylamine backbone is a privileged substructure found in a wide variety of G protein-coupled receptor (GPCR) ligands. This includes both endogenous neurotransmitters and active pharmaceutical agents. More than 20 structurally unique heterocyclic phenethylamine derivatives...

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Veröffentlicht in:ACS Med Chem Lett
Hauptverfasser: Porter, Matthew R., Xiao, Haiyan, Wang, Jing, Smith, Sylvia B., Topczewski, Joseph J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2019
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792158/
https://ncbi.nlm.nih.gov/pubmed/31620230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00225
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