SIRPα expression delineates subsets of intratumoral monocyte/macrophages with different functional and prognostic impact in follicular lymphoma

Signal regulatory protein-α (SIRPα) is a key member of the “do-not-eat-me” signaling pathway, but its biological role and clinical relevance in B-cell NHL is relatively unknown. Using biopsy specimens from follicular lymphoma (FL), we identified three subsets (CD14(+)SIRPα(hi), CD14(−)SIRPα(low), an...

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Bibliografske podrobnosti
izdano v:Blood Cancer J
Main Authors: Chen, Ya-Ping, Kim, Hyo Jin, Wu, Hongyan, Price-Troska, Tammy, Villasboas, Jose C., Jalali, Shahrzad, Feldman, Andrew L., Novak, Anne J., Yang, Zhi-Zhang, Ansell, Stephen M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791879/
https://ncbi.nlm.nih.gov/pubmed/31611550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-019-0246-0
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