Mass Cytometry Analysis Reveals that Specific Intratumoral CD4(+) T Cell Subsets Correlate with Patient Survival in Follicular Lymphoma

Follicular lymphoma (FL) is an indolent B cell malignancy characterized by an extensive but poorly functional T cell infiltrate in the tumor microenvironment. Using mass cytometry, we identified at least 12 subsets of intratumoral CD4(+) T cells, 3 of which were unique to FL biopsies versus control...

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Pubblicato in:Cell Rep
Autori principali: Yang, Zhi-Zhang, Jin Kim, Hyo, Villasboas, Jose C., Price-Troska, Tammy, Jalali, Shahrzad, Wu, Hongyan, Luchtel, Rebecca A., Polley, Mei-Yin C., Novak, Anne J., Ansell, Stephen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402596/
https://ncbi.nlm.nih.gov/pubmed/30784598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.01.085
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