A docking-based structural analysis of geldanamycin-derived inhibitor binding to human or Leishmania Hsp90

Leishmaniasis is a neglected disease that affects millions of individuals around the world. Regardless of clinical form, treatment is based primarily on the use of pentavalent antimonials. However, such treatments are prolonged and present intense side effects, which lead to patient abandonment in m...

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Udgivet i:Sci Rep
Main Authors: Palma, Luana Carneiro, Ferreira, Luiz Felipe Gomes Rebello, Petersen, Antonio Luis de Oliveira Almeida, Dias, Beatriz Rocha Simões, Menezes, Juliana Perrone Bezerra de, Moreira, Diogo Rodrigo de Magalhães, Hernandes, Marcelo Zaldini, Veras, Patricia Sampaio Tavares
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791876/
https://ncbi.nlm.nih.gov/pubmed/31611575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51239-0
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