CCL2 promotes macrophages-associated chemoresistance via MCPIP1 dual catalytic activities in multiple myeloma

We previously showed that the chemokine CCL2 can recruit macrophages (Mφs) to the bone marrow (BM) in multiple myeloma (MM) and that myeloma-associated Mφs are important in drug resistance. Here, we explore the role of increased CCL2 expression in the BM microenvironment of MM and elucidate the unde...

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Pubblicato in:Cell Death Dis
Autori principali: Xu, Ruyi, Li, Yi, Yan, Haimeng, Zhang, Enfan, Huang, Xi, Chen, Qingxiao, Chen, Jing, Qu, Jianwei, Liu, Yang, He, Jingsong, Yi, Qing, Cai, Zhen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791869/
https://ncbi.nlm.nih.gov/pubmed/31611552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2012-4
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