CCL2 promotes macrophages-associated chemoresistance via MCPIP1 dual catalytic activities in multiple myeloma

We previously showed that the chemokine CCL2 can recruit macrophages (Mφs) to the bone marrow (BM) in multiple myeloma (MM) and that myeloma-associated Mφs are important in drug resistance. Here, we explore the role of increased CCL2 expression in the BM microenvironment of MM and elucidate the unde...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Xu, Ruyi, Li, Yi, Yan, Haimeng, Zhang, Enfan, Huang, Xi, Chen, Qingxiao, Chen, Jing, Qu, Jianwei, Liu, Yang, He, Jingsong, Yi, Qing, Cai, Zhen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791869/
https://ncbi.nlm.nih.gov/pubmed/31611552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2012-4
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