CCL2 promotes macrophages-associated chemoresistance via MCPIP1 dual catalytic activities in multiple myeloma

We previously showed that the chemokine CCL2 can recruit macrophages (Mφs) to the bone marrow (BM) in multiple myeloma (MM) and that myeloma-associated Mφs are important in drug resistance. Here, we explore the role of increased CCL2 expression in the BM microenvironment of MM and elucidate the unde...

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Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Xu, Ruyi, Li, Yi, Yan, Haimeng, Zhang, Enfan, Huang, Xi, Chen, Qingxiao, Chen, Jing, Qu, Jianwei, Liu, Yang, He, Jingsong, Yi, Qing, Cai, Zhen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791869/
https://ncbi.nlm.nih.gov/pubmed/31611552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2012-4
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