Endothelial cell pyroptosis plays an important role in Kawasaki disease via HMGB1/RAGE/cathespin B signaling pathway and NLRP3 inflammasome activation

Kawasaki disease (KD) is the most common cause of pediatric cardiac disease in developed countries, and can lead to permanent coronary artery damage and long term sequelae such as coronary artery aneurysms. Given the prevalence and severity of KD, further research is warranted on its pathophysiology...

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Vydáno v:Cell Death Dis
Hlavní autoři: Jia, Chang, Zhang, Jian, Chen, Huanwen, Zhuge, Yingzhi, Chen, Huiqiao, Qian, Fanyu, Zhou, Kailiang, Niu, Chao, Wang, Fangyan, Qiu, Huixian, Wang, Zhenquan, Xiao, Jian, Rong, Xing, Chu, Maoping
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791856/
https://ncbi.nlm.nih.gov/pubmed/31611559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2021-3
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