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Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction

Antitumor drug development based on the concept of intervening in the antioxidant system of cancer cells has been gaining increased interest. In this study, we propose a promising strategy for cancer treatment using modulation of oxidative stress by suppression of glutathione S-transferases (GSTs),...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fujitani, Naoki, Yoneda, Akihiro, Takahashi, Motoko, Takasawa, Akira, Aoyama, Tomoyuki, Miyazaki, Tadaaki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791853/
https://ncbi.nlm.nih.gov/pubmed/31611630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51462-9
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