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Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction

Antitumor drug development based on the concept of intervening in the antioxidant system of cancer cells has been gaining increased interest. In this study, we propose a promising strategy for cancer treatment using modulation of oxidative stress by suppression of glutathione S-transferases (GSTs),...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Fujitani, Naoki, Yoneda, Akihiro, Takahashi, Motoko, Takasawa, Akira, Aoyama, Tomoyuki, Miyazaki, Tadaaki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791853/
https://ncbi.nlm.nih.gov/pubmed/31611630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51462-9
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