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Redirecting the immune response towards immunoprotective domains of a DNABII protein resolves experimental otitis media

The chronicity and recurrence of many bacterial diseases is largely attributable to the presence of a biofilm, and eradication of these structures is confounded by an extracellular DNA-rich matrix. DNABII proteins, including integration host factor (IHF), are critical components of the matrix formed...

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Detalhes bibliográficos
Publicado no:NPJ Vaccines
Main Authors: Novotny, L. A., Goodman, S. D., Bakaletz, L. O.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791836/
https://ncbi.nlm.nih.gov/pubmed/31632744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-019-0137-1
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